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Catalog No. | A19824 |
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Product Name | TAB3 Rabbit mAb |
Supplier Name | ABclonal, Inc. |
Brand Name | Abclonal |
Synonyms | NAP1; MAP3K7IP3 |
Gene Name | TAB3 |
Protein Name | TAB3 |
Uniprot/Swissprot ID | Q8N5C8 |
Entrez GeneID | 257397 |
Clone | ARC2350 |
Clonality | Monoclonal |
Source/Host | Rabbit |
Applications | WB |
Reactivity | Human, Mouse |
Conjugate | Unconjugated |
Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Additional information
Ship from Country | USA |
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Size | 20 ul, 100 ul, 200 ul, 50 ul |
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