TAB3 Rabbit mAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

TAB3 Rabbit mAb

$148.00$548.00

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$148.00$548.00

NAP1; MAP3K7IP3

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SKU: A19824
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Catalog No. A19824
Product NameTAB3 Rabbit mAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms NAP1; MAP3K7IP3
Gene Name TAB3
Protein Name TAB3
Uniprot/Swissprot ID Q8N5C8
Entrez GeneID 257397
Clone ARC2350
Clonality Monoclonal
Source/Host Rabbit
Applications WB
Reactivity Human, Mouse
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Additional information

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USA

Size

20 ul, 100 ul, 200 ul, 50 ul

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