SMMHC/MYH11 Rabbit mAb (A4064)

SMMHC/MYH11 Rabbit mAb (A4064)

SMMHC/MYH11 Rabbit mAb (A4064)

$148.00$548.00

In stock

$148.00$548.00

Abclonal SMMHC/MYH11 Rabbit mAb (Catalog Number: A4064) encoded by this gene is a smooth muscle myosin belonging to the myosin heavy chain family. The gene product is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits.

Store
SKU: A4064
Clear
View cart
Catalog No. A4064
Product NameSMMHC/MYH11 Rabbit mAb (A4064)
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms AAT4; FAA4; SMHC; SMMHC; VSCM2; SMMS-1
Gene Name MYH11
Protein Name MYH11
Uniprot/Swissprot ID P35749
Entrez GeneID 4629
Clone ARC51911
Clonality Monoclonal
Source/Host Rabbit
Applications WB, IHC-P, IF/ICC
Reactivity Human, Mouse, Rat
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

A4064: SMMHC/MYH11 Rabbit mAb

The protein encoded by this gene is a smooth muscle myosin belonging to the myosin heavy chain family. The gene product is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It functions as a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. A chromosomal rearrangement involving this gene is associated with acute myeloid leukemia of the M4Eo subtype. Mutations in this gene are associated with visceral myopathy, megacystis-microcolon-intestinal hypoperistalsis syndrome 2, and familial thoracic aortic aneurysm 4.

Immunogen Information about SMMHC/MYH11 Rabbit mAb (A4064)

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1160-1313 of human SMMHC/MYH11 (NP_002465.1).
Sequence:DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL
Gene ID:4629
Swiss prot:P35749
Synonyms:AAT4; FAA4; SMHC; SMMHC; VSCM2; SMMS-1; SMMHC/MYH11
Calculated MW:227kDa
Observed MW:250kDa

Images of SMMHC/MYH11 Rabbit mAb (A4064)

Western blot analysis of lysates from Mouse lung, using SMMHC/SMMHC/MYH11 Rabbit mAb (A4064) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 3min.

Western blot analysis of lysates from Rat lung, using SMMHC/SMMHC/MYH11 Rabbit mAb (A4064) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit (RM00021).
Exposure time: 3min.

Immunohistochemistry analysis of SMMHC/MYH11 in paraffin-embedded human colon carcinoma using SMMHC/MYH11 Rabbit mAb (A4064) at dilution of 1:8000 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.

Immunohistochemistry analysis of SMMHC/MYH11 in paraffin-embedded human colon using SMMHC/MYH11 Rabbit mAb (A4064) at dilution of 1:8000 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.

Immunohistochemistry analysis of SMMHC/MYH11 in paraffin-embedded human placenta using SMMHC/MYH11 Rabbit mAb (A4064) at dilution of 1:8000 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.

Immunohistochemistry analysis of SMMHC/MYH11 in paraffin-embedded mouse kidney using SMMHC/MYH11 Rabbit mAb (A4064) at dilution of 1:8000 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.

Confocal imaging of paraffin-embedded Rat small intestine using SMMHC/MYH11 Rabbit mAb (A4064, dilution 1:800) followed by a further incubation with Cy3 Goat Anti-Rabbit IgG (H+L) (AS007, dilution 1:500)(Red).DAPI was used for nuclear staining (Blue). Objective: 40x. Perform high pressure antigen retrieval with 0.01 M citRate buffer (pH 6.0) prior to IF staining.

Confocal imaging of paraffin-embedded Human colon using SMMHC/MYH11 Rabbit mAb (A4064, dilution 1:800) followed by a further incubation with Cy3 Goat Anti-Rabbit IgG (H+L) (AS007, dilution 1:500)(Red).DAPI was used for nuclear staining (Blue). Objective: 40x. Perform high pressure antigen retrieval with 0.01 M citRate buffer (pH 6.0) prior to IF staining.

Please remember our product information: SMMHC/MYH11 Rabbit mAb (Catalog Number: A4064) Abclonal

Additional information

Ship from Country

USA

Size

20 ul, 100 ul, 200 ul, 50 ul

No more offers for this product!