SERCA2/ATP2A2 Rabbit mAb
$148.00 – $548.00
DD; DAR; ATP2B; SERCA2
- Details & Specifications
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| Catalog No. | A11692 |
|---|---|
| Product Name | SERCA2/ATP2A2 Rabbit mAb |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | DD; DAR; ATP2B; SERCA2 |
| Gene Name | ATP2A2 |
| Protein Name | ATP2A2 |
| Uniprot/Swissprot ID | P16615 |
| Entrez GeneID | 488 |
| Clone | ARC0679 |
| Clonality | Monoclonal |
| Source/Host | Rabbit |
| Applications | WB, IP |
| Reactivity | Human, Mouse, Rat |
| Conjugate | Unconjugated |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of the skeletal muscle. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Other types of mutations in this gene have been associated with various forms of muscular dystrophies. Alternative splicing results in multiple transcript variants encoding different isoforms.
