Recombinant Human PAK2 kinase domain Enzyme

Recombinant Human PAK2 kinase domain Enzyme: BP001574-K0105 Syd Labs

Recombinant Human PAK2 kinase domain Enzyme

$340.00$8,000.00

In stock

$340.00$8,000.00

Syd Labs Recombinant Human PAK2 kinase domain Enzyme BP001574-K0105, Specific activity of Recombinant Human PAK2 kinase domain (PAK2KD) Enzyme: 85,806 pmoles/min/ug. Analysis of enzymatic activity was performed according to the Zlyte assay protocol (Invitrogen).

SKU: BP001574-K0105
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Catalog No. BP001574-K0105
Product NameRecombinant Human PAK2 kinase domain Enzyme
Supplier Name Syd Labs, Inc.
Brand Name Syd Labs
Synonyms PAK2 kinase domain
Source E. coli-derived.
Formulation 1 ug/ml in Storage Buffer of 25 mM Tris-HCl pH 8.0, 150 mM NaCl, 10% glycerol, 5 mM DTT.
Shipping The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Note Conditions of optimal PAK2KD Enzyme performance should be determined experimentally by the investigator.
Order Offline Phone: 1-617-401-8149Fax: 1-617-606-5019Email: message@sydlabs.comOr leave a message with a formal purchaseorder (PO) Or credit card.

Description

BP001574-K0105: Recombinant Human PAK2 kinase domain Enzyme

Background

Human PAK2 kinase (UniProt: Q13177; NCBI: NM_002577) belongs to a family of p21-activated kinases. These serine/threonine kinases are regulated by the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK2 is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.

BP001574-K0105: Recombinant Human PAK2 kinase domain (PAK2KD) Enzyme

Source: E. coli-derived.
Predicted molecular mass: 33,510 Da. PAK2KD is fully phosphorylated at T402 and partially phosphorylated at additional sites with measured mass of 33,593 (1P), 33,673 (2P), 33,753 (3P), and 33,834 (4P).
Specific activity: 85,806 pmoles/min/ug. Analysis of enzymatic activity was performed according to the Zlyte assay protocol (Invitrogen).
Formulation: 1 ug/ml in Storage Buffer of 25 mM Tris-HCl pH 8.0, 150 mM NaCl, 10% glycerol, 5 mM DTT.
Applications: Enzymatic studies, inhibitor screen, and selectivity profiling; High concentration available for crystallization.

Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.

Please remember our product information: Recombinant Human PAK2 kinase domain Enzyme: BP001574-K0105 Syd Labs

Additional information

Ship from Country

USA

Size

10 ug, 1 mg, 100 ug

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