Recombinant Human FSH A/B Protein

Recombinant Human FSH A/B Protein: BP000035-GD9 Syd Labs

Recombinant Human FSH A/B Protein

$300.00$1,200.00

In stock

$300.00$1,200.00

Syd Labs Recombinant Human FSH A/B Protein BP000035-GD9, The activity of Follicle-Stimulating Hormone (FSH) α/β is measured in a human FSH receptor transfected HEK 293 cells. The ED50 for this effect is 0.1-0.4 ng/ml.

SKU: BP000035-GD9
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Catalog No. BP000035-GD9
Product NameRecombinant Human FSH A/B Protein
Supplier Name Syd Labs, Inc.
Brand Name Syd Labs
Synonyms Follicle-stimulating hormone
Source Chinese Hamster Ovary cell line, CHO-derived.
Formulation Lyophilized from a 0.2 um filtered solution in PBS, pH 7.4.
Purity > 95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Endotoxin <1.0 EU per 1 ug of the protein by the LAL method.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Note Conditions of optimal FSH Protein performance should be determined experimentally by the investigator.
Order Offline Phone: 1-617-401-8149Fax: 1-617-606-5019Email: message@sydlabs.comOr leave a message with a formal purchaseorder (PO) Or credit card.

Description

BP000035-GD9: Recombinant Human FSH A/B Protein

Background

Follicle-stimulating hormone (FSH) is a hormone found in humans and other animals. It is synthesized and secreted by gonadotrophs of the anterior pituitary gland. FSH is a glycoprotein. Each monomeric unit is a protein molecule with a sugar attached to it; two of these make the full, functional protein. The protein dimer contains 2 polypeptide units (1)., labeled alpha and beta subunits. The alpha subunits contain 92 amino acids. The beta subunits vary. FSH has a beta subunit of 118 amino acids (FSHβ), which confers its specific biologic action and is responsible for interaction with the FSH-receptor. The sugar part of the hormone is composed of fucose, galactose, mannose, galactosamine, glucosamine, and sialic acid, the latter being critical for its biologic half-life. The half-life of FSH is 3-4 hours. FSH regulates the development, growth, pubertal maturation, and reproductive processes of the human body.

BP000035-GD9: Recombinant Human FSH α/β Protein

Source: Chinese Hamster Ovary cell line, CHO-derived.
Human FSH α (Ala25 Ser116), Accession # P01215
Human FSH β (Cys21 Glu129), Accession # P01225
N-terminal sequence analysis: Ala25 (FSH α) & Cys21 (FSH β),
Predicted molecular mass: 10 kDa (FSH α) & 12 kDa (FSH β).
SDS-PAGE: About 25 kDa, reducing conditions.
The FSH α/β activity is measured in a human FSH receptor transfected HEK 293 cells. The ED50 for this effect is 0.1-0.4 ng/ml.
Endotoxin Level: <1.0 EU per 1 ug of the protein by the LAL method. Purity > 95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Formulation: Lyophilized from a 0.2 um filtered solution in PBS, pH 7.4.
Reconstitution: Reconstitute at 100 ug/ml in sterile PBS containing at least 0.1% human or bovine serum albumin.

Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.

Please remember our product information: Recombinant Human FSH A/B Protein: BP000035-GD9 Syd Labs

Additional information

Ship from Country

USA

Size

100 IU, 200 IU, 600 IU

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