Anti-Myc-Tag Monoclonal Antibody(Clone 9E10) | PA000002.mf

Catalog No.	PA000002.mf
Product Name	Recombinant Anti-Myc-Tag Mouse Fab Fragment (Clone 9E10)
Supplier Name	Syd Labs, Inc.
Brand Name	Syd Labs
Synonyms	Anti-c-Myc Antibody, c-Myc Antibody (9E10), Clone 9E10
Summary	The Recombinant Anti-Myc-Tag Mouse Fab Fragment (Clone 9E10) is produced in mammalian cells. It consists of mouse variable regions and mouse IgG1 kappa constant regions.
Clone	9E10.
Specificity/Sensitivity	c-Myc tagged proteins and Myc tag expression cells.
Applications	ELISA, flow cytometry, immunoblotting, immunoprecipitation, immunocytochemistry, immunofluorescence, chromatin immunoprecipitation, electron microscopy, supershift assays, protein purification if conjugated with agarose or magnetic beads, and isotype controls.
Reactivity	Human, Mouse, Rat, Others.
Purification	The c-Myc-tag antibody was affinity-purified from supernatant of mammalian cells cultured in a chemically defined medium by affinity-chromatography using protein A.
Form Of Antibody	1 mg/ml in 1x PBS.
Purity	>95% by SDS-PAGE under reducing conditions.
Shipping	The Recombinant Anti-Myc-Tag Mouse Fab Fragment (Clone 9E10) is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. 1 month from date of receipt, 2 to 8°C as supplied. 3 months from date of receipt, -20°C to -70°C as supplied.
Note	Recombinant Myc-Tag monoclonal antibodies (clone 9E10) with various isotypes; low prices for bulk order.
Order Offline	Phone: 1-617-401-8149 Fax: 1-617-606-5022 Email: message@sydlabs.com Or leave a message with a formal purchase order (PO) Or credit card.

Description

PA000002.mf: Anti-Myc-Tag Mouse Fab Fragment (Clone 9E10), Recombinant

The recombinant anti-Myc-Tag mouse IgG1 monoclonal antibody (clone 9E10) is produced in mammalian cells. It consists of mouse variable regions and mouse IgG1 kappa constant regions.

References of Anti-Myc-Tag Monoclonal Antibody (Clone 9E10)

1. Truncated mini LRP1 transports cargo from luminal to basolateral side across the blood brain barrier
Laura Fritzen, et al.Fluids Barriers CNS. 2024 Sep 17;21(1):74. doi: 10.1186/s12987-024-00573-1. PMID: 39289695; PMCID: PMC11409491
“Transporting drugs across the blood-brain barrier (BBB) remains a major challenge in developing central nervous system (CNS) therapies. While previous research has utilized nanoparticle formulations to target BBB receptors, the precise mechanisms governing their entry and distribution within the CNS parenchyma are largely unexplored. This study investigates the novel pathways facilitating therapeutic cargo movement from the luminal to the basolateral side of the BBB.”

2. A multi-Fc-species system for recombinant antibody production
Sandrine Moutel, et al.BMC Biotechnol. 2009 Feb 26;9:14. doi: 10.1186/1472-6750-9-14. PMID: 19245715; PMCID: PMC2654441
“The lack of functional validation in large-scale genomic and proteomic projects has driven the demand for highly versatile and specific antibodies. While in vitro antibody phage display is a rapid, animal-free method for selecting single-chain Fv antibodies, these recombinant formats often underperform compared to natural equivalents. To address this, researchers have developed novel vector systems that fuse scFv fragments to immunoglobulin Fc domains, significantly enhancing their sensitivity and practical applications.”

3. Apolipoprotein L1-Specific Antibodies Detect Endogenous APOL1 inside the Endoplasmic Reticulum and on the Plasma Membrane of Podocytes
Suzie J Scales, et al.J Am Soc Nephrol. 2020 Sep;31(9):2044-2064. doi: 10.1681/ASN.2019080829. PMID: 32764142; PMCID: PMC7461670
“The APOL1 protein is naturally expressed within the endothelia and podocytes of human kidneys. Genetic variations in the APOL1 gene, specifically variants G1 and G2, are strongly associated with the high prevalence of nondiabetic chronic kidney disease in African American populations. Current hypotheses regarding APOL1-mediated cytotoxicity in podocytes suggest that these pathogenic variants may disrupt vital functions across different subcellular compartments.”

4. Human Cytomegalovirus Infection Elicits a Glycoprotein M (gM)/gN-Specific Virus-Neutralizing Antibody Response
Masako Shimamura, et al.J Virol. 2006 May;80(9):4591-600. doi: 10.1128/JVI.80.9.4591-4600.2006. PMID: 16611919; PMCID: PMC1471997
“Human cytomegalovirus (HCMV) is a highly prevalent pathogen that, while often asymptomatic in healthy individuals, can cause life-threatening complications in immunocompromised patients. The host’s antiviral defense involves a complex neutralizing antibody response targeting various surface glycoproteins encoded by the virus. This study demonstrates that the gM/gN glycoprotein complex can stimulate a robust virus-neutralizing antibody response, making it a promising candidate for future prophylactic CMV vaccine development.”

5. A Highly Functional Synthetic Phage Display Library Containing over 40 Billion Human Antibody Clones
Marcel Weber, et al.PLoS One. 2014 Jun 20;9(6):e100000. doi: 10.1371/journal.pone.0100000. PMID: 24950200; PMCID: PMC4065035
“The effectiveness of synthetic antibody phage display libraries in generating high-affinity binders depends heavily on their overall size, cloning quality, and specific design features. In this study, researchers present the construction and validation of a massive combinatorial library containing over 40 billion human single-chain fragment variable (scFv) clones. This highly functional library consistently yielded potent and specific antibodies against diverse target antigens, providing a valuable tool for both academic research and therapeutic development.”

For more technical references or data sheets regarding the Anti-Myc-Tag Monoclonal Antibody (Clone 9E10) formats, please contact our scientific support team at message@sydlabs.com.

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Please remember our product information: Recombinant Anti-Myc-Tag Mouse Fab Fragment (Clone 9E10): PA000002.mf Syd Labs