RAD51A Polyclonal Antibady

RAD51A Polyclonal Antibady

$250.00$350.00

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$250.00$350.00

Conditions of optimal RAD51A polyclonal antibady performance should be determined experimentally by the investigator.

SKU: PA000200-R12-3400
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Catalog No. PA000200-R12-3400
Product NameRAD51A Polyclonal Antibady
Supplier Name Syd Labs, Inc.
Brand Name Syd Labs
Synonyms DNA repair protein RAD51 homolog 1 Antibody
Specificity/Sensitivity RAD51A Antibody detects endogenous levels of RAD51A.
Reactivity Human, Mouse.
Immunogen The antiserum was produced against synthesized peptide derived from human RAD51A.
Purification The antibody was affinity-purified from rabbit anti-serum by immunogenic peptide affinity-chromatography.
Form Of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol.
Stability & Storage Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
Note Conditions of optimal RAD51A antibody performance should be determined experimentally by the investigator.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

PA000200-R12-3400: RAD51A Polyclonal Antibady
Background
DNA repair protein RAD51 homolog 1, also known as RAD51A, is a human gene. The Rad51 gene,HsRAD51, is a homolog of RecA of Escherichia coli and functions in recombination and DNA repair.BRCA1 and BRCA2 proteins form a complex with Rad51, and these genes are thought to participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair.1 RAD51 is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis.2
Other RAD51A Antibody:
RAD51A Polyclonal Antibady

Additional information

Ship from Country

USA

Size

100 ug, 50 ug

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