Phospho-STAT6-Y641 Rabbit mAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

Phospho-STAT6-Y641 Rabbit mAb

$148.00$548.00

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$148.00$548.00

STAT6B; STAT6C; D12S1644; IL-4-STAT

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SKU: AP1390
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Catalog No. AP1390
Product NamePhospho-STAT6-Y641 Rabbit mAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms STAT6B; STAT6C; D12S1644; IL-4-STAT
Gene Name STAT6
Protein Name STAT6
Uniprot/Swissprot ID P42226
Entrez GeneID 6778
Clone ARC57025
Clonality Monoclonal
Source/Host Rabbit
Applications WB, IHC-P
Reactivity Human, Mouse, Rat
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.

Additional information

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USA

Size

20 ul, 100 ul, 200 ul, 50 ul

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