Phospho-PDHA1-S293 Rabbit mAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

Phospho-PDHA1-S293 Rabbit mAb

$148.00$548.00

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$148.00$548.00

PDHA; PDHAD; PHE1A; E1alpha; PDHCE1A

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SKU: AP1022
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Catalog No. AP1022
Product NamePhospho-PDHA1-S293 Rabbit mAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms PDHA; PDHAD; PHE1A; E1alpha; PDHCE1A
Gene Name PDHA1
Protein Name PDHA1
Uniprot/Swissprot ID P08559
Entrez GeneID 5160
Clone ARC53489
Clonality Monoclonal
Source/Host Rabbit
Applications WB, IF/ICC, IP
Reactivity Human, Mouse, Rat
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Additional information

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USA

Size

20 ul, 100 ul, 200 ul, 50 ul

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