Phospho-Chk1 (S280) Rabbit mAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

Phospho-Chk1 (S280) Rabbit mAb

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$148.00$548.00

CHK1

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SKU: AP1426
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Catalog No. AP1426
Product NamePhospho-Chk1 (S280) Rabbit mAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms CHK1
Gene Name CHEK1
Protein Name CHEK1
Uniprot/Swissprot ID O14757
Entrez GeneID 1111
Clone ARC3123
Clonality Monoclonal
Source/Host Rabbit
Applications WB
Reactivity Human
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene.

Additional information

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USA

Size

20 ul, 100 ul, 200 ul, 50 ul

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