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Catalog No. | AP1426 |
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Product Name | Phospho-Chk1 (S280) Rabbit mAb |
Supplier Name | ABclonal, Inc. |
Brand Name | Abclonal |
Synonyms | CHK1 |
Gene Name | CHEK1 |
Protein Name | CHEK1 |
Uniprot/Swissprot ID | O14757 |
Entrez GeneID | 1111 |
Clone | ARC3123 |
Clonality | Monoclonal |
Source/Host | Rabbit |
Applications | WB |
Reactivity | Human |
Conjugate | Unconjugated |
Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene.
Additional information
Ship from Country | USA |
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Size | 20 ul, 100 ul, 200 ul, 50 ul |
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