PD1 PE-Cyanine7(125384)

PD1 PE-Cyanine7(125384)

$230.00$645.00

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$230.00$645.00

PD1 PE-Cyanine7

SKU: 125384
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Catalog No. 125384
Product NamePD1 PE-Cyanine7(125384)
Supplier Name Caprico Biotechnologies, Inc.
Brand Name Caprico
Accession No. NC_000002.12
Protein Name PD1
Uniprot/Swissprot ID Q15116
Entrez GeneID 5133
Primary/Secondary Primary
Clone 8E10
Clonality Monoclonal
Source/Host Mouse
Applications FC
Reactivity Human
Immunogen PD1 transfected HEK293 cells
Form Of Antibody PBS pH 7.2, 0.2% (w/v) BSA, 0.09% (w/v) sodium azide
Conjugate PE-Cyanine7
Purity >95%
Stability & Storage 2-8oC
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Description

125384:PD1 PE-Cyanine7(125384)

The clone 6D5, a mouse monoclonal antibody selectively binds with a 50-55 kD cell surface protein commonly known as Programmed cell death 1 (PD-1) or CD279, a member of the immunoglobulin superfamily. PD-1 expression is mostly observed in activated T cells and B cells, and also in dendritic cells. PD-1 signals via binding its two ligands, PD-L1 and PD-L2. Upon ligand binding, PD-1 signaling inhibits T-cell activation, leading to reduced proliferation, cytokine production, and T cell death. Blocking of PD-1 by its antibody restores T cells immunity against tumor and infectious agents. PD-1-blockade based immunotherapy is, therefore, highly clinically useful against various types of cancers and infectious diseases.
Please remember our product information: PD1 PE-Cyanine7(125384) catalog number: 125384 Caprico Biotechnologies

Additional information

Ship from Country

USA

Size

100 test, 200 Test, 25 test

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