PD1 Biotin(112751)
$405.00
Caprico Biotechnologies PD1 Biotin catalog number: 112751，The clone DCN.70, a mouse monoclonal antibody selectively binds with a k type I membrane protein commonly known as CD276, a member of B7-H3 immunoregulatory family.
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| Catalog No. | 112751 |
|---|---|
| Product Name | PD1 Biotin(112751) |
| Supplier Name | Caprico Biotechnologies, Inc. |
| Brand Name | Caprico |
| Accession No. | NC_000002.12 |
| Protein Name | PD1 |
| Uniprot/Swissprot ID | Q15116 |
| Gene ID | 5133 |
| Primary/Secondary | Primary |
| Clone | 6D5 |
| Clonality | Monoclonal |
| Source/Host | Mouse |
| Reactivity | Human |
| Immunogen | PD1 transfected HEK293 cells |
| Form Of Antibody | PBS pH 7.2, 0.09% sodium azide |
| Conjugate | Biotin |
| Purity | >95% |
| Stability & Storage | 2-8oC |
| Note | Products will be shipped from the warehouse in Georgia. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Phone: 1-617-401-8149 Fax: 1-617-606-5060 Email: message@sydlabs.com Orleave a message with a formal purchase order (PO) Or credit card. |
Description
112751：PD1 Biotin(112751)
The clone DCN.70, a mouse monoclonal antibody selectively binds with a k type I membrane protein commonly known as CD276, a member of B7-H3 immunoregulatory family. It is not expressed by lymphocytes or granulocytes but weakly expressed on resting monocytes. Increased expression is observed on monocytes derived dendritic cells as well as in a variety of cancer types, including breast, pancreatic, and ovarian cancer. CD276 expression has been correlated with poor survival in ovarian cancer subjects. CD276 blockade, especially when combined with an anti-PD-1 blockade, is a promising strategy for the treatment of B7-H3-expressing NSCLCs that arerefractory to anti-PD-1 therapy, making CD276 a promising clinical molecular target.
Please remember our product information: PD1 Biotin(112751) catalog number: 112751 Caprico Biotechnologies