PD-1/CD279 Rabbit mAb
$148.00 – $548.00
PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1
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| Catalog No. | A23007 |
|---|---|
| Product Name | PD-1/CD279 Rabbit mAb |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1 |
| Gene Name | PDCD1 |
| Protein Name | PDCD1 |
| Uniprot/Swissprot ID | Q15116 |
| Gene ID | 5133 |
| Clone | ARC56369 |
| Clonality | Monoclonal |
| Source/Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Conjugate | Unconjugated |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity.
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