Mouse Noggin Protein (NOG-MM001)
$310.50 – $1,035.00
KACTUS Biosystems Mouse Noggin Protein (NOG-MM001) (catalog No. NOG-MM001) is expressed from HEK293 without tag.It contains Gln28-Cys232.
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| Catalog No. | NOG-MM001 |
|---|---|
| Product Name | Mouse Noggin Protein (NOG-MM001) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Species | Mouse |
| Source | HEK293 |
| Accession | P97466 |
| Product Tag | No Tag |
| Biotinylated | no |
| Exact Sequence | Gln28-Cys232 |
| Molecular Weight | The protein has a predicted MW of 23.07 kDa. Due to glycosylation, the protein migrates to 28-33 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS, 100mM L-arginine (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
NOG-MM001: Mouse Noggin Protein (NOG-MM001)
Noggin is an antagonist of bone morphogenetic proteins (BMP), being indispensable for certain developmental events.Noggin expression positively correlated with EGFR expression in both GC cell line models and The Cancer Genome Atlas human GC cohort. Targeting EGFR and its downstream pathways diminished cell proliferation which was promoted by Noggin. Noggin promotes the proliferation of GC cells by upregulating EGFR and enhancing a vicious circle formed by β‑catenin, EGFR, ERK and Akt.
Please remember our product information: Mouse Noggin Protein (NOG-MM001) catalog number: NOG-MM001 KACTUS Biosystems
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug, 500 ug |