Mouse LAIR1/CD305 Protein (LAI-MM1R1)
$182.70 – $607.50
KACTUS Biosystems Mouse LAIR1/CD305 Protein (LAI-MM1R1) (catalog No. LAI-MM1R1) is expressed from HEK293 with His tag at the C-Terminus.It contains Gln22-Tyr141.
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Catalog No. | LAI-MM1R1 |
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Product Name | Mouse LAIR1/CD305 Protein (LAI-MM1R1) |
Supplier Name | KACTUS Biosystems |
Brand Name | KACTUS Biosystems |
Synonyms | CD305; HLAIR1; LAIR1; LAIR-1 |
Species | Mouse |
Source | HEK293 |
Accession | Q8BG84-1 |
Product Tag | C-His |
Biotinylated | no |
Exact Sequence | Gln22-Tyr141 |
Molecular Weight | The protein has a predicted MW of 14.6 kDa. Due to glycosylation, the protein migrates to 30-42 kDa based on Tris-Bis PAGE result. |
Form | Lyophilized |
Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
Endotoxin | Less than 1EU per μg by the LAL method. |
Shipping | Shipped at ambient temperature. |
Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.;-20 to -80°C for 3-6 months in unopened state after reconstitution.;2-8°C for 2-7 days after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
LAI-MM1R1: Mouse LAIR1/CD305 Protein (LAI-MM1R1)
LAIR1 (leukocyte-associated Ig-like receptor-1, designated CD305) is an approximately 40 kDa type I transmembrane inhibitory glycoprotein belonging to the Ig superfamily.LAIR1 functions as an inhibitory receptor that plays a constitutive negative regulatory role on cytolytic function of natural killer (NK) cells, B-cells and T-cells. Activation by Tyr phosphorylation results in recruitment and activation of the phosphatases PTPN6 and PTPN11. It also reduces the increase of intracellular calcium evoked by B-cell receptor ligation.
Please remember our product information: Mouse LAIR1/CD305 Protein (LAI-MM1R1) catalog number: LAI-MM1R1 KACTUS Biosystems
Additional information
Ship from Country | USA |
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Size | 100 ug, 500 ug |