Mouse KLRG1 Protein (KLR-MM2G1)
$283.50 – $945.00
KACTUS Biosystems Mouse KLRG1 Protein (KLR-MM2G1) (catalog No. KLR-MM2G1) is expressed from HEK293 with hFc tag at the N-Terminus.It contains Gln57-Tyr188.
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| Catalog No. | KLR-MM2G1 |
|---|---|
| Product Name | Mouse KLRG1 Protein (KLR-MM2G1) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | KLRG1; CLEC15A; MAFA; MAFAL; 2F1; CLEC15AMAFA-LIKE; MGC13600 |
| Species | Mouse |
| Source | HEK293 |
| Accession | O88713 |
| Product Tag | N-hFc |
| Biotinylated | no |
| Exact Sequence | Gln57-Tyr188 |
| Molecular Weight | The protein has a predicted MW of 42.3 kDa. Due to glycosylation, the protein migrates to 43-50 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
KLR-MM2G1: Mouse KLRG1 Protein (KLR-MM2G1)
Immune homeostasis requires the tight, tissue-specific control of the different CD4 Foxp3 regulatory T (Treg) cell populations. The cadherin-binding inhibitory receptor killer cell lectin-like receptor G1 (KLRG1) is expressed by a subpopulation of Treg cells with GATA3 effector phenotype.Lack of KLRG1 on Treg cells conferred on them a competitive advantage in the gut, but not in lymphoid organs. Hence, although absence of KLRG1 is not enough to increase intestinal Treg cells in KLRG1 knockout mice, KLRG1 ligation reduces T-cell receptor signals and the competitive fitness of individual Treg cells in the intestine.
Please remember our product information: Mouse KLRG1 Protein (KLR-MM2G1) catalog number: KLR-MM2G1 KACTUS Biosystems
