Mouse Integrin alpha 2B beta 3 (ITGA2B&ITGB3) Heterodimer Protein (ITG-MM12B)
$337.50 – $1,125.00
KACTUS Biosystems Mouse Integrin alpha 2B beta 3 (ITGA2B&ITGB3) Heterodimer Protein (ITG-MM12B) (catalog No. ITG-MM12B) is expressed from HEK293 with His tag at the C-Terminus.It contains Leu32-Arg988(ITGA2B) acidic tail & Glu26-Asp717(ITGB3) basic tail.
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| Catalog No. | ITG-MM12B |
|---|---|
| Product Name | Mouse Integrin alpha 2B beta 3 (ITGA2B&ITGB3) Heterodimer Protein (ITG-MM12B) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | ITGA2B&ITGB3; ITGA2B; ITGB3 |
| Species | Mouse |
| Source | HEK293 |
| Accession | Q9QUM0(ITGA2B)&O54890(ITGB3) |
| Product Tag | C-His |
| Biotinylated | no |
| Exact Sequence | Leu32-Arg988(ITGA2B) acidic tail & Glu26-Asp717(ITGB3) basic tail |
| Molecular Weight | The protein has a predicted MW of 109.80 kDa (ITGA2B)&80.80 kDa (ITGB3). Due to glycosylation, the protein migrates to 90-113 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
ITG-MM12B: Mouse Integrin alpha 2B beta 3 (ITGA2B&ITGB3) Heterodimer Protein (ITG-MM12B)
Glanzmann thrombasthenia (GT) is characterized by mucocutaneous bleeding due to platelets that fail to aggregate in response to physiologic stimuli. GT, a rare inherited disease, is caused by quantitative or qualitative deficiencies of αIIbβ3, an integrin receptor for adhesive proteins. Coded by the ITGA2B and ITGB3 genes, αIIbβ3 mediates platelet-to-platelet attachment, aggregation and clot retraction.
Please remember our product information: Mouse Integrin alpha 2B beta 3 (ITGA2B&ITGB3) Heterodimer Protein (ITG-MM12B) catalog number: ITG-MM12B KACTUS Biosystems
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug, 500 ug |