Mouse Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer Protein (ITG-MM1AB)
$337.50 – $1,125.00
KACTUS Biosystems Mouse Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer Protein (ITG-MM1AB) (catalog No. ITG-MM1AB) is expressed from HEK293 with His tag at the C-Terminus.It contains Tyr27-Thr1129(ITGA2) acidic tail & Gln21-Asp728(ITGB1) basic tail.
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| Catalog No. | ITG-MM1AB |
|---|---|
| Product Name | Mouse Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer Protein (ITG-MM1AB) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | ITGA2&ITGB1; ITGA2; ITGB1; |
| Species | Mouse |
| Source | HEK293 |
| Accession | Q62469(ITGA2)&P09055-1(ITGB1) |
| Product Tag | C-His |
| Biotinylated | no |
| Exact Sequence | Tyr27-Thr1129(ITGA2) acidic tail & Gln21-Asp728(ITGB1) basic tail |
| Molecular Weight | The protein has a predicted MW of 126.60 kDa(ITGA2)&82.80 kDa(ITGB1). Due to glycosylation, the protein migrates to 128-138 kDa(ITGA2)&105-115 kDa(ITGB1) based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
ITG-MM1AB: Mouse Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer Protein (ITG-MM1AB)
Integrin alpha 2 beta 1 is a positive regulator of collagenase (MMP-1) and collagen alpha 1(I) gene expression.HOS cells normally lacking alpha 2 beta 1 integrin were forced to express it, and this prevented the down-regulation in the levels of alpha 1 (I) collagen mRNA when cells were grown inside collagen gels. The data indicate that the level of MMP-1 expression is regulated by the collagen receptor alpha 2 beta 1 integrin.
Please remember our product information: Mouse Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer Protein (ITG-MM1AB) catalog number: ITG-MM1AB KACTUS Biosystems