Mouse Integrin alpha 1 beta 1 (ITGA1&ITGB1) Heterodimer Protein (ITG-MM1A1)
$337.50 – $1,125.00
KACTUS Biosystems Mouse Integrin alpha 1 beta 1 (ITGA1&ITGB1) Heterodimer Protein (ITG-MM1A1) (catalog No. ITG-MM1A1) is expressed from HEK293 with His tag at the C-Terminus.It contains Phe29-Pro1141(ITGA1) acidic tail&Gln21-Asp728(ITGB1) basic tail.
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| Catalog No. | ITG-MM1A1 |
|---|---|
| Product Name | Mouse Integrin alpha 1 beta 1 (ITGA1&ITGB1) Heterodimer Protein (ITG-MM1A1) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Species | Mouse |
| Source | HEK293 |
| Accession | Q3V3R4(ITGA1)&P09055-1(ITGB1) |
| Product Tag | C-His |
| Biotinylated | no |
| Exact Sequence | Phe29-Pro1141(ITGA1)acidic tail & Gln21-Asp728(ITGB1)basic tail |
| Molecular Weight | The protein has a predicted MW of 129.00 kDa (ITGA1)&82.80 kDa (ITGB1). Due to glycosylation, the protein migrates to 140-200 kDa (ITGA1) and 100-115 kDa (ITGB1) based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
ITG-MM1A1: Mouse Integrin alpha 1 beta 1 (ITGA1&ITGB1) Heterodimer Protein (ITG-MM1A1)
Integrin α1β1 is a heterodimer of the Integrin subunits alpha 1 and beta 1 and is one of four collagen‑binding integrins, it preferentially binds Collagens I, IV, VI, XIII and XVI, but also binds Laminin. Integrin α1β1 is widely expressed in mesenchyme and the immune system, as well as a minority of epithelial tissues. It can suppresse EGFR signaling, increase expression of Caveolin-1, reduce production of reactive oxygen species, regulate collagen expression, regulate MMP collagenase and gelatinase activity, and mediates the renal basement membrane disorder Alport syndrome.
Please remember our product information: Mouse Integrin alpha 1 beta 1 (ITGA1&ITGB1) Heterodimer Protein (ITG-MM1A1) catalog number: ITG-MM1A1 KACTUS Biosystems
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug, 500 ug |