Mouse IGFBP-3R Protein (IGF-MM23R)
$270.00 – $900.00
KACTUS Biosystems Mouse IGFBP-3R Protein (IGF-MM23R) (catalog No. IGF-MM23R) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gly39-Arg204.
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| Catalog No. | IGF-MM23R |
|---|---|
| Product Name | Mouse IGFBP-3R Protein (IGF-MM23R) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | IGFBP-3R; GFBP3R; LOC124446; TMEM219 |
| Species | Mouse |
| Source | HEK293 |
| Accession | Q9D123-1 |
| Product Tag | C-hFc |
| Biotinylated | no |
| Exact Sequence | Gly39-Arg204 |
| Molecular Weight | The protein has a predicted MW of 44.4 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
IGF-MM23R: Mouse IGFBP-3R Protein (IGF-MM23R)
Insulin-like growth factor-binding protein-3 (IGFBP-3) is a multifunctional protein known for modulating mitogenic and metabolic actions of IGFs as well as exerting a variety of biological actions not involving IGF. IGFBP-3 inhibits airway inflammation and hyper-responsiveness via an IGF-independent mechanism that involves activation of IGFBP-3R signaling and cross-talk with NF-κB signaling. The IGFBP-3/IGFBP-3R system therefore plays a pivotal role in the pathogenesis of asthma and can serve as a newly identified potential therapeutic target for this debilitating disease.
Please remember our product information: Mouse IGFBP-3R Protein (IGF-MM23R) catalog number: IGF-MM23R KACTUS Biosystems
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug, 500 ug |