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Mouse Glypican 1/GPC1 Protein (GPC-MM111)

Mouse Glypican 1/GPC1 Protein (GPC-MM111)

Mouse Glypican 1/GPC1 Protein (GPC-MM111)

$283.50$945.00

In stock

$283.50$945.00

KACTUS Biosystems Mouse Glypican 1/GPC1 Protein (GPC-MM111) (catalog No. GPC-MM111) is expressed from HEK293 with His tag at the C-Terminus.It contains Asp24-Ser529.

SKU: GPC-MM111
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Catalog No. GPC-MM111
Product NameMouse Glypican 1/GPC1 Protein (GPC-MM111)
Supplier Name KACTUS Biosystems
Brand Name KACTUS Biosystems
Synonyms Glypican-1; FLJ38078; GPC1
Species Mouse
Source HEK293
Accession Q9QZF2
Product Tag C-His
Biotinylated no
Exact Sequence Asp24-Ser529
Molecular Weight The protein has a predicted MW of 56.8 kDa. Due to glycosylation, the protein migrates to 65-68 kDa based on Tris-Bis PAGE result.
Form Lyophilized
Formulation Lyophilized from 0.22μm filtered solution in 50mM Tris,150mM NaCl (pH 7.5). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per μg by the LAL method.
Shipping Shipped at ambient temperature.
Stability & Storage '-20 to -80°C for 12 months as supplied from date of receipt.;-20 to -80°C for 3-6 months in unopened state after reconstitution.;2-8°C for 2-7 days after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

GPC-MM111: Mouse Glypican 1/GPC1 Protein (GPC-MM111)

CAR-T cells targeting glypican-1 (GPC1)-specific human and murine CAR-T cells generated from our original anti-human/mouse GPC1 antibody showed strong antitumor effects in xenogeneic and syngeneic mouse models, respectively. Importantly, the murine CAR-T cells enhanced endogenous T cell responses against a non-GPC1 tumor antigen through the mechanism of antigen-spreading and showed synergistic antitumor effects with anti-PD-1 antibody without any adverse effects in syngeneic models.

Please remember our product information: Mouse Glypican 1/GPC1 Protein (GPC-MM111) catalog number: GPC-MM111 KACTUS Biosystems

Additional information

Ship from Country

USA

Size

100 ug, 500 ug

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