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Mouse GARP&Latent TGF beta 1 Complex Protein (GAT-MM101)

Mouse GARP&Latent TGF beta 1 Complex Protein (GAT-MM101)

Mouse GARP&Latent TGF beta 1 Complex Protein (GAT-MM101)

$283.50$945.00

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$283.50$945.00

KACTUS Biosystems Mouse GARP&Latent TGF beta 1 Complex Protein (GAT-MM101) (catalog No. GAT-MM101) is expressed from HEK293 with His tag at the N-Terminus.It contains Ala18-Leu628(GARP)&Leu30-Ser390(Latent TGF beta 1).

SKU: GAT-MM101
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Catalog No. GAT-MM101
Product NameMouse GARP&Latent TGF beta 1 Complex Protein (GAT-MM101)
Supplier Name KACTUS Biosystems
Brand Name KACTUS Biosystems
Synonyms LRRC32; GARP; LAP; TGF-beta-1; LRRC32&TGF-beta 1; LRRC32&TGFB1
Species Mouse
Source HEK293
Accession G3XA59(GARP)&P04202(Latent TGF beta 1)
Product Tag N-His
Biotinylated no
Exact Sequence Ala18-Leu628(GARP) & Leu30-Ser390(Latent TGF beta 1)
Molecular Weight The protein has a predicted MW of 66.6 kDa (GARP)&41.3 kDa (Latent TGF beta 1). Due to glycosylation, the protein migrates to 70-80 kDa (GARP)&13 kDa&42-50 kDa (Latent TGF beta 1) based on Tris-Bis PAGE result.
Form Lyophilized
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per μg by the LAL method.
Shipping Shipped at ambient temperature.
Stability & Storage '-20 to -80°C for 12 months as supplied from date of receipt.;-20 to -80°C for 3-6 months in unopened state after reconstitution.;2-8°C for 2-7 days after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

GAT-MM101: Mouse GARP&Latent TGF beta 1 Complex Protein (GAT-MM101)

GARP&Latent TGF Beta is a complex found on surface of many types of cells. In Tregs, GARP is involved in TCR-mediated activation of Latent TGF-β and thus promoting secretion and activation of TGF-β. Integrin αvβ8 on the surface of immune cells and other cells recognizes RGD in LAP, resulting in the release of mature TGF-β from the TGF-β&GARP complex.

Please remember our product information: Mouse GARP&Latent TGF beta 1 Complex Protein (GAT-MM101) catalog number: GAT-MM101 KACTUS Biosystems

Additional information

Ship from Country

USA

Size

100 ug, 500 ug

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