[KO Validated] c-Myc Rabbit mAb
$148.00 – $548.00
MRTL; MYCC; c-Myc; bHLHe39
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| Catalog No. | A19032 |
|---|---|
| Product Name | [KO Validated] c-Myc Rabbit mAb |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | MRTL; MYCC; c-Myc; bHLHe39 |
| Gene Name | MYC |
| Protein Name | MYC |
| Uniprot/Swissprot ID | P01106 |
| Entrez GeneID | 4609 |
| Clone | ARC0412 |
| Clonality | Monoclonal |
| Source/Host | Rabbit |
| Applications | WB, ChIP, CUT&Tag |
| Reactivity | Human, Mouse |
| Conjugate | Unconjugated |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini.
