Kinesin light chain 1 (KLC1) Rabbit mAb

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Kinesin light chain 1 (KLC1) Rabbit mAb

$148.00$548.00

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$148.00$548.00

KLC; KNS2; KNS2A

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SKU: A19249
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Catalog No. A19249
Product NameKinesin light chain 1 (KLC1) Rabbit mAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms KLC; KNS2; KNS2A
Gene Name KLC1
Protein Name KLC1
Uniprot/Swissprot ID Q07866
Entrez GeneID 3831
Clone ARC2409
Clonality Monoclonal
Source/Host Rabbit
Applications WB
Reactivity Human, Mouse, Rat
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named “kinesin 2”, this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature and/or biological validity of most of these variants have not been determined.

Additional information

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USA

Size

20 ul, 100 ul, 200 ul, 50 ul

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