[KD Validated] JNK1 Rabbit mAb

Catalog No.	A21888
Product Name	[KD Validated] JNK1 Rabbit mAb
Supplier Name	ABclonal, Inc.
Brand Name	Abclonal
Synonyms	JNK; JNK1; PRKM8; SAPK1; JNK-46; JNK1A2; SAPK1c; JNK21B1/2
Gene Name	MAPK8
Protein Name	MAPK8
Uniprot/Swissprot ID	P45983
Entrez GeneID	5599
Clone	ARC2908
Clonality	Monoclonal
Source/Host	Rabbit
Applications	WB
Reactivity	Human, Mouse, Rat
Conjugate	Unconjugated
Note	Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline	Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.

Additional information

Ship from Country	USA
Size	20 ul, 100 ul, 200 ul, 50 ul

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