Integrin alpha 6 (ITGA6/CD49f) Rabbit mAb
$148.00 – $548.00
JEB6; CD49f; VLA-6; ITGA6A; ITGA6B
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| Catalog No. | A19070 |
|---|---|
| Product Name | Integrin alpha 6 (ITGA6/CD49f) Rabbit mAb |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | JEB6; CD49f; VLA-6; ITGA6A; ITGA6B |
| Gene Name | ITGA6 |
| Protein Name | ITGA6 |
| Uniprot/Swissprot ID | P23229 |
| Entrez GeneID | 3655 |
| Clone | ARC51523 |
| Clonality | Monoclonal |
| Source/Host | Rabbit |
| Applications | WB, FC |
| Reactivity | Human, Mouse, Rat |
| Conjugate | Unconjugated |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants.
