Infliximab Biosimilar, L234A L235A P329G (LALAPG) Fc Silent Mutant

Infliximab Biosimilar, L234A L235A P329G (LALAPG) Fc Silent Mutant

$375.00

In stock

$375.00

Infliximab Biosimilar, L234A L235A P329G (LALAPG) Fc Silent Mutant. Infliximab biosimilar CHO stable cell line is available for licensing to manufacture the Infliximab biosimilar protein. The research grade infliximab biosimilar protein is for research use only (RUO). Recombinant human IgG1 isotype controls are available.

SKU: C011P.LA
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Catalog No. C011P.LA
Product NameInfliximab Biosimilar, L234A L235A P329G (LALAPG) Fc Silent Mutant
Supplier Name Syd Labs, Inc.
Brand Name Syd Labs
Synonyms Anti-TNF alpha Chimeric Monoclonal Antibody
Summary Recombinant Chimeric IgG1 Monoclonal Antibody.
Isotype Human IgG1 kappa.
Source/Host The monoclonal antibody Infliximab biosimilar was produced in the Infliximab biosimilar CHO stable cell line.
Specificity/Sensitivity The monoclonal antibody Infliximab biosimilar specifically binds to the human TNF alpha.
Form Of Antibody 0.2 uM filtered solution, pH 7.2, no stabilizers or preservatives.
Endotoxin < 1 EU per 1 mg of the protein by the LAL method.
Purity >95% by SDS-PAGE under reducing conditions and HPLC.
Shipping The Infliximab Biosimilar, L234A L235A P329G (LALAPG) Fc Silent Mutant is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied.
Note Infliximab biosimilar CHO stable cell line is available for licensing to manufacture the Infliximab biosimilar protein. The research grade infliximab biosimilar protein is for research use only (RUO). Recombinant human IgG1 isotype controls are available.
Order Offline Phone: 1-617-401-8149 Fax: 1-617-606-5022 Email: message@sydlabs.com Orleave a message with a formal purchase order (PO) Or credit card.

Description

C011P.LA: Infliximab Biosimilar, L234A L235A P329G (LALAPG) Fc Silent Mutant

Recombinant Chimeric IgG1 Monoclonal Antibody.

Background

Infliximab, a chimeric anti-TNF-α monoclonal antibody, is used to treat psoriasis, Crohn’s disease, ankylosing spondylitis, psoriatic arthritis, rheumatoid arthritis, and ulcerative colitis. Infliximab interferes TNF-α from binding to its receptor in the cell.

Mainly produced by activated macrophages (M1), Tumor necrosis factor (TNF, cachexin, cachectin, tumor necrosis factor alpha, TNFα) plays important roles in the regulation of autoimmune reaction.

Syd Labs also provides the following anti-TNF antibody biosimilar protein:
Adalimumab Biosimilar, research grade

Syd Labs also provides the following research grade antibody biosimilar proteins:
Bevacizumab Biosimilar, research grade (VEGF-A)
Ranibizumab Biosimilar, research grade (VEGF-A, Fab produced in E. coli)
Cetuximab Biosimilar, research grade (HER1, ErbB-1, EGFR)
Panitumumab Biosimilar, research grade (HER1, ErbB-1, EGFR)
Trastuzumab Biosimilar, research grade (HER2, ErbB-2, c-neu)
Pertuzumab Biosimilar, research grade (HER2, ErbB-2, c-neu)
Infliximab biosimilar, research grade (TNF alpha)
Adalimumab biosimilar, research grade (TNF alpha)
Rituximab biosimilar, research grade (CD20)
Denosumab biosimilar, research grade (RANKL, RANK ligand, OPGL, TNFSF11, CD254, TRANCE, ODF)
Palivizumab Biosimilar, research grade (RSV)
Omalizumab biosimilar, research grade (IgE)
Eculizumab biosimilar, research grade (C5)

Please remember our product information: Infliximab Biosimilar, L234A L235A P329G (LALAPG) Fc Silent Mutant: C011P.LA Syd Labs

Additional information

Ship from Country

USA

Size

0.5 mg

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