Human TRAIL R2/DR5/TNFRSF10B Protein (TRL-HM4R2)
$196.20 – $652.50
KACTUS Biosystems Human TRAIL R2/DR5/TNFRSF10B Protein (TRL-HM4R2) (catalog No. TRL-HM4R2) is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Ile56-Glu182.
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| Catalog No. | TRL-HM4R2 |
|---|---|
| Product Name | Human TRAIL R2/DR5/TNFRSF10B Protein (TRL-HM4R2) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | CD262; DR5; DR5TRICK2B; Fas-like protein; KILLER/DR5; TNFRSF10B; TRAIL R2; TRAIL receptor 2; TRAILR2; TRICK2; TRICK2A; TRICKB; ZTNFR9; KILLER |
| Species | Human |
| Source | HEK293 |
| Accession | O14763-1 |
| Product Tag | C-His-Avi |
| Biotinylated | no |
| Exact Sequence | Ile56-Glu182 |
| Molecular Weight | The protein has a predicted MW of 17.2 kDa. Due to glycosylation, the protein migrates to 20-25 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
TRL-HM4R2: Human TRAIL R2/DR5/TNFRSF10B Protein (TRL-HM4R2)
DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.
Please remember our product information: Human TRAIL R2/DR5/TNFRSF10B Protein (TRL-HM4R2) catalog number: TRL-HM4R2 KACTUS Biosystems
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug, 500 ug |