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Human TRAIL R1/DR4/TNFRSF10A Protein (TRL-HM2R1)
$196.20 – $652.50
KACTUS Biosystems Human TRAIL R1/DR4/TNFRSF10A Protein (TRL-HM2R1) (catalog No. TRL-HM2R1) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Pro34-Asn239.
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| Catalog No. | TRL-HM2R1 |
|---|---|
| Product Name | Human TRAIL R1/DR4/TNFRSF10A Protein (TRL-HM2R1) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | DR4; CD261; TNFRSF10A; TRAIL-R; APO2; TRAIL R1; MGC9365 |
| Species | Human |
| Source | HEK293 |
| Accession | O00220 |
| Product Tag | C-hFc |
| Biotinylated | no |
| Exact Sequence | Pro34-Asn239 |
| Molecular Weight | The protein has a predicted MW of 48.8 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.; -20 to -80°C for 3-6 months in unopened state after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
TRL-HM2R1: Human TRAIL R1/DR4/TNFRSF10A Protein (TRL-HM2R1)
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) induces apoptosis selectively via its interaction with the death receptors TRAILR1/DR4 and TRAILR2/DR5 in a wide range of cancers, while sparing normal cells. Despite its tremendous potential for cancer therapeutics, the translation of TRAIL into the clinic has been confounded by TRAIL-resistant cancer populations.
Please remember our product information: Human TRAIL R1/DR4/TNFRSF10A Protein (TRL-HM2R1) catalog number: TRL-HM2R1 KACTUS Biosystems
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