Human Thyroid Peroxidase Protein (TPO-HM101)
$270.00 – $900.00
KACTUS Biosystems Human Thyroid Peroxidase Protein (TPO-HM101) (catalog No. TPO-HM101) is expressed from HEK293 with His tag at the C-Terminus.It contains Phe19-Arg846.
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| Catalog No. | TPO-HM101 |
|---|---|
| Product Name | Human Thyroid Peroxidase Protein (TPO-HM101) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | TPO; THPO; MGC163194; MGDF; MKCSF; ML; MPLLG; THCYT1; MGDFC-mpl ligand; MK-CSF; MPL ligand; Thrombopoietin; TPOMKCSF |
| Species | Human |
| Source | HEK293 |
| Accession | P07202-1 |
| Product Tag | C-His |
| Biotinylated | no |
| Exact Sequence | Phe19-Arg846 |
| Molecular Weight | The protein has a predicted MW of 90.6 kDa. Due to glycosylation, the protein migrates to 95-105 kDa based on Tris-Bis PAGE result. |
| Form | Liquid |
| Formulation | Supplied as 0.22μm filtered solution in 20mM Tris, 500mM NaCl, 10% Glycerol (pH 7.4). |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped with dry ice. |
| Stability & Storage | Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
TPO-HM101: Human Thyroid Peroxidase Protein (TPO-HM101)
Thyroid peroxidase, also called thyroperoxidase (TPO) or iodide peroxidase that encodes a 933 amino-acid residue (aa) molecule with a single membrane-spanning region. Thyroid peroxidase plays a key role in thyroid hormone synthesis by catalyzing both the iodination of tyrosine residues to form monoiodotyrosine (MIT) and diiodotyrosine (DIT) residues and the coupling of iodotyrosine residues in Tg, resulting in the formation of T3 and T4. It is a frequent epitope of autoantibodies in autoimmune thyroid disease, for example, the expression of thyroid peroxidase is lost in papillary thyroid carcinoma.
Please remember our product information: Human Thyroid Peroxidase Protein (TPO-HM101) catalog number: TPO-HM101 KACTUS Biosystems
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug, 500 ug |
