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Human Siglec-5/CD170 Protein (SIG-HM205)
$189.00 – $630.00
KACTUS Biosystems Human Siglec-5/CD170 Protein (SIG-HM205) (catalog No. SIG-HM205) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Glu17-Thr434.
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Catalog No. | SIG-HM205 |
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Product Name | Human Siglec-5/CD170 Protein (SIG-HM205) |
Supplier Name | KACTUS Biosystems |
Brand Name | KACTUS Biosystems |
Synonyms | CD170; CD33 antigen-like 2; CD33L2; OBBP2; Siglec5; SIGLEC5; OB-BP2 |
Species | Human |
Source | HEK293 |
Accession | O15389 |
Product Tag | C-hFc |
Biotinylated | no |
Exact Sequence | Glu17-Thr434 |
Molecular Weight | The protein has a predicted MW of 73.1 kDa. Due to glycosylation, the protein migrates to 90-115 kDa based on Tris-Bis PAGE result. |
Form | Lyophilized |
Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
Endotoxin | Less than 1EU per μg by the LAL method. |
Shipping | Shipped at ambient temperature. |
Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.; -20 to -80°C for 3-6 months in unopened state after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
SIG-HM205: Human Siglec-5/CD170 Protein (SIG-HM205)
Interactions between endothelial selectins and the leukocyte counter-receptor PSGL1 mediates leukocyte recruitment to inflammation sites. PSGL1 is highly sialylated, making it a potential ligand for Siglec-5, a leukocyte-receptor that recognizes sialic acid structures. Binding assays using soluble Siglec-5 variants (sSiglec-5/C4BP and sSiglec-5/Fc) revealed a dose- and calcium-dependent binding to PSGL1.
Please remember our product information: Human Siglec-5/CD170 Protein (SIG-HM205) catalog number: SIG-HM205 KACTUS Biosystems
Additional information
Ship from Country | USA |
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Size | 100 ug, 500 ug |
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