Human Siglec-10 Protein (SIG-HM210)
$283.50 – $945.00
KACTUS Biosystems Human Siglec-10 Protein (SIG-HM210) (catalog No. SIG-HM210) is expressed from HEK293 with His tag at the C-Terminus.It contains Met17-Thr546.
- Details & Specifications
- References
| Catalog No. | SIG-HM210 |
|---|---|
| Product Name | Human Siglec-10 Protein (SIG-HM210) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | SLG2; SIGLEC10; MGC126774; PRO940 |
| Species | Human |
| Source | HEK293 |
| Accession | Q96LC7-1 |
| Product Tag | C-His |
| Biotinylated | no |
| Exact Sequence | Met17-Thr546 |
| Molecular Weight | The protein has a predicted MW of 59.2 kDa. Due to glycosylation, the protein migrates to 70-79 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in 20mM PB, 150mM NaCl, 25mM L-arginine (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
SIG-HM210: Human Siglec-10 Protein (SIG-HM210)
Siglec-10 is a ligand for CD52, the target of the therapeutic monoclonal antibody Alemtuzumab. It is also reported to bind to Vascular adhesion protein 1 (VAP-1) and to the co-stimulatory molecule CD24 also known as HSA (Heat-stable antigen).Siglecs (sialic acid binding Ig-like lectins) are I-type lectins that belong to the immunoglobulin superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by a varying number of Ig-like C2-type domains. Siglecs 5-11 constitute the CD33/Siglec-3 related group, and are differentially expressed in the hematopoietic system.
Please remember our product information: Human Siglec-10 Protein (SIG-HM210) catalog number: SIG-HM210 KACTUS Biosystems