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Human SEZ6 Protein (SEZ-HM106)
$270.00 – $900.00
KACTUS Biosystems Human SEZ6 Protein (SEZ-HM106) (catalog No. SEZ-HM106) is expressed from HEK293 with His tag at the C-Terminus.It contains Leu20-His925.
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| Catalog No. | SEZ-HM106 |
|---|---|
| Product Name | Human SEZ6 Protein (SEZ-HM106) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | SEZ-6; SEZ6; BSRPC; BSRP-C |
| Species | Human |
| Source | HEK293 |
| Accession | Q53EL9-1 |
| Product Tag | C-His |
| Biotinylated | no |
| Exact Sequence | Leu20-His925 |
| Molecular Weight | The protein has a predicted MW of 98.9 kDa. Due to glycosylation, the protein migrates to 145-150 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
SEZ-HM106: Human SEZ6 Protein (SEZ-HM106)
Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform of Sez6 is cleaved by the β-amyloid precursor protein cleavage enzyme 1 (BACE1), resulting in Sez6 extracellular domain shedding from the neuron surface.
Please remember our product information: Human SEZ6 Protein (SEZ-HM106) catalog number: SEZ-HM106 KACTUS Biosystems
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