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Human RNF43 Protein (RNF-HM143)

Human RNF43 Protein (RNF-HM143)

Human RNF43 Protein (RNF-HM143)

$283.50$945.00

In stock

$283.50$945.00

KACTUS Biosystems Human RNF43 Protein (RNF-HM143) (catalog No. RNF-HM143) is expressed from HEK293 with His tag at the C-terminal.It contains Gly24-Tyr197.

SKU: RNF-HM143
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Catalog No. RNF-HM143
Product NameHuman RNF43 Protein (RNF-HM143)
Supplier Name KACTUS Biosystems
Brand Name KACTUS Biosystems
Species Human
Source HEK293
Accession Q68DV7-1
Product Tag C-His
Biotinylated no
Exact Sequence Gly24-Tyr197
Molecular Weight The protein has a predicted MW of 20.14 kDa. Due to glycosylation, the protein migrates to 28-38 kDa based on Tris-Bis PAGE result.
Form Liquid
Formulation Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per μg by the LAL method.
Shipping Shipped with dry ice.
Stability & Storage Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

RNF-HM143: Human RNF43 Protein (RNF-HM143)

RNF43 (E3 ubiquitin-protein ligase RNF43 or RING-type E3 ubiquitin transferase RNF43) functions as a tumor suppressor, by exerting a predominant negative feedback mechanism in the Wnt/β-catenin signaling pathway. RNF43 inhibits Wnt/beta-catenin signaling by ubiquitinating Frizzled receptor and targeting it to the lysosomal pathway for degradation.

Please remember our product information: Human RNF43 Protein (RNF-HM143) catalog number: RNF-HM143 KACTUS Biosystems

Additional information

Ship from Country

USA

Size

100 ug, 500 ug

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