Human PILRA Protein (PRA-HM201)
$243.00 – $810.00
KACTUS Biosystems Human PILRA Protein (PRA-HM201) (catalog No. PRA-HM201) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln20-Ala197.
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| Catalog No. | PRA-HM201 |
|---|---|
| Product Name | Human PILRA Protein (PRA-HM201) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | PILRA; FDF03; PILRalpha; PILR-alpha |
| Species | Human |
| Source | HEK293 |
| Accession | Q9UKJ1 |
| Product Tag | C-hFc |
| Biotinylated | no |
| Exact Sequence | Gln20-Ala197 |
| Molecular Weight | The protein has a predicted MW of 47 kDa. Due to glycosylation, the protein migrates to 60-68 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
PRA-HM201: Human PILRA Protein (PRA-HM201)
Alzheimer’s disease (AD) is a neurodegenerative disease characterized by a progressive decline in cognitive performance; Mild Cognitive Impairment (MCI) is instead an objective decline in cognitive performance that does not reach pathology. Paired immunoglobulin-like type 2 receptor alpha (PILRA) is a cell surface inhibitory receptor that was recently suggested to be involved in AD pathogenesis. In particular, the arginine-to-glycine substitution in position 78 (R78, rs1859788) was shown to be protective against AD.
Please remember our product information: Human PILRA Protein (PRA-HM201) catalog number: PRA-HM201 KACTUS Biosystems