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Human PD-L1/B7-H1 Protein (PDL-HM210)
$120.00 – $400.00
KACTUS Biosystems Human PD-L1/B7-H1 Protein (PDL-HM210) (catalog No. PDL-HM210) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Phe19-Arg238.
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Catalog No. | PDL-HM210 |
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Product Name | Human PD-L1/B7-H1 Protein (PDL-HM210) |
Supplier Name | KACTUS Biosystems |
Brand Name | KACTUS Biosystems |
Synonyms | CD274; PDL1; PD-L1; PD-L1B7 homolog 1;B7-H; B7H1; B7-H1; PDCD1L1; PDCD1LG1 |
Species | Human |
Source | HEK293 |
Accession | Q9NZQ7-1 |
Product Tag | C-hFc |
Biotinylated | no |
Exact Sequence | Phe19-Arg238 |
Molecular Weight | The protein has a predicted MW of 52 kDa. Due to glycosylation, the protein migrates to 68-80 kDa based on Tris-Bis PAGE result. |
Activity | Immobilized Human PD-1, mFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Human PD-L1, hFc Tag with the EC50 of 0.93ug/ml determined by ELISA (QC Test). The affinity constant of 2.356 uM as determined in SPR assay (Biacore T200). See testing image for detail. |
Form | Lyophilized |
Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
Endotoxin | Less than 1EU per μg by the LAL method. |
Shipping | Shipped at ambient temperature. |
Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.; -20 to -80°C for 3-6 months in unopened state after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
PDL-HM210: Human PD-L1/B7-H1 Protein (PDL-HM210)
B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance.
Please remember our product information: Human PD-L1/B7-H1 Protein (PDL-HM210) catalog number: PDL-HM210 KACTUS Biosystems
Additional information
Ship from Country | USA |
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Size | 100 ug, 500 ug |
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