Human PD-L1/B7-H1 Protein (PDL-HM210)

Catalog No.	PDL-HM210
Product Name	Human PD-L1/B7-H1 Protein (PDL-HM210)
Supplier Name	KACTUS Biosystems
Brand Name	KACTUS Biosystems
Synonyms	CD274; PDL1; PD-L1; PD-L1B7 homolog 1;B7-H; B7H1; B7-H1; PDCD1L1; PDCD1LG1
Species	Human
Source	HEK293
Accession	Q9NZQ7-1
Product Tag	C-hFc
Biotinylated	no
Exact Sequence	Phe19-Arg238
Molecular Weight	The protein has a predicted MW of 52 kDa. Due to glycosylation, the protein migrates to 68-80 kDa based on Tris-Bis PAGE result.
Activity	Immobilized Human PD-1, mFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Human PD-L1, hFc Tag with the EC50 of 0.93ug/ml determined by ELISA (QC Test). The affinity constant of 2.356 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Form	Lyophilized
Formulation	Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per μg by the LAL method.
Shipping	Shipped at ambient temperature.
Stability & Storage	'-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Note	Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline	Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

PDL-HM210: Human PD-L1/B7-H1 Protein (PDL-HM210)

B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance.

Please remember our product information: Human PD-L1/B7-H1 Protein (PDL-HM210) catalog number: PDL-HM210 KACTUS Biosystems

Additional information

Ship from Country	USA
Size	100 ug, 500 ug

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