Catalog No.	NPC-HM102
Product Name	Human NPC2 Protein (NPC-HM102)
Supplier Name	KACTUS Biosystems
Brand Name	KACTUS Biosystems
Species	Human
Source	HEK293
Accession	P61916-1
Product Tag	C-His
Biotinylated	no
Exact Sequence	Glu20-Leu151
Molecular Weight	The protein has a predicted MW of 15.67 kDa. Due to glycosylation, the protein migrates to 21-24 kDa and 27-35 kDa kDa based on Tris-Bis PAGE result.
Form	Liquid
Formulation	Supplied as 0.22μm filtered solution in PBS (pH 7.4).
Purity	> 95% as determined by Tris-Bis PAGE
Endotoxin	Less than 1EU per μg by the LAL method.
Shipping	Shipped with dry ice.
Stability & Storage	Valid for 12 months from date of receipt when stored at -80°C.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Note	Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline	Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

NPC-HM102: Human NPC2 Protein (NPC-HM102)

The Niemann Pick type C (NPC) proteins, NPC1 and NPC2, are involved in the lysosomal storage disease, NPC disease. The formation of a NPC1⁻NPC2 protein⁻protein complex is believed to be necessary for the transfer of cholesterol and lipids out of the late endosomal (LE)/lysosomal (Lys) compartments. Mutations in either NPC1 or NPC2 can lead to an accumulation of cholesterol and lipids in the LE/Lys, the primary phenotype of the NPC disease.

Please remember our product information: Human NPC2 Protein (NPC-HM102) catalog number: NPC-HM102 KACTUS Biosystems

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