Human NKp30/NCR3/CD337 Protein (NKP-HM230)
$216.00 – $720.00
KACTUS Biosystems Human NKp30/NCR3/CD337 Protein (NKP-HM230) (catalog No. NKP-HM230) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Leu19-Thr138.
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| Catalog No. | NKP-HM230 |
|---|---|
| Product Name | Human NKp30/NCR3/CD337 Protein (NKP-HM230) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | CD337; LY117; NCR3; NKp30; 1C7; MALS |
| Species | Human |
| Source | HEK293 |
| Accession | AAH52582 |
| Product Tag | C-hFc |
| Biotinylated | no |
| Exact Sequence | Leu19-Thr138 |
| Molecular Weight | The protein has a predicted MW of 39.8 kDa. Due to glycosylation, the protein migrates to 53-60 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
NKP-HM230: Human NKp30/NCR3/CD337 Protein (NKP-HM230)
NKp30, along with NKp44 and NKp46, constitute a group of receptors termed “Natural Cytotoxicity Receptors”. These receptors play a major role in triggering NK-mediated killing of most tumor cells lines.NKp30 stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG which promote DC maturation.
Please remember our product information: Human NKp30/NCR3/CD337 Protein (NKP-HM230) catalog number: NKP-HM230 KACTUS Biosystems
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug, 500 ug |