Human Nectin-3/CD113 Protein (NEC-HM403)
$283.50 – $945.00
KACTUS Biosystems Human Nectin-3/CD113 Protein (NEC-HM403) (catalog No. NEC-HM403) is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly58-Asp400.
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| Catalog No. | NEC-HM403 |
|---|---|
| Product Name | Human Nectin-3/CD113 Protein (NEC-HM403) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | CD113; CDw113; FLJ90624; PPR3; PVRL3; PVRR3; PRR3 |
| Species | Human |
| Source | HEK293 |
| Accession | Q9NQS3 |
| Product Tag | C-His-Avi |
| Biotinylated | no |
| Exact Sequence | Gly58-Asp400 |
| Molecular Weight | The protein has a predicted MW of 40.6 kDa. Due to glycosylation, the protein migrates to 68-82 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in 20mM PB, 250mM NaCl (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
NEC-HM403: Human Nectin-3/CD113 Protein (NEC-HM403)
The Nectin family has at least four members (Nectin-1‑4), all of which show alternate splicing, a transmembrane (TM) region (except for Nectin-1 gamma), and three extracellular Ig-domains. Nectins are highly homologous to the human receptor for poliovirus, and as such, have been alternatively-named poliovirus receptor-related proteins. They do not, however, appear to bind poliovirus. Nectin-3 (also named PRR3, CD113, and PVRL3) is an 83 kDa, type I TM glycoprotein. Its precursor is 549 amino acids (aa) in length. It contains an extended signal sequence of 57 aa, an extracellular domain (ECD) of 347 aa, a transmembrane segment of 21 aa (aa 405-425), and a cytoplasmic region of 124 amino acids.
Please remember our product information: Human Nectin-3/CD113 Protein (NEC-HM403) catalog number: NEC-HM403 KACTUS Biosystems