Human LILRB4/CD85k/ILT3 Protein (LIL-HM2B4)
$283.50 – $945.00
KACTUS Biosystems Human LILRB4/CD85k/ILT3 Protein (LIL-HM2B4) (catalog No. LIL-HM2B4) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln22-Arg256.
- Details & Specifications
- References
| Catalog No. | LIL-HM2B4 |
|---|---|
| Product Name | Human LILRB4/CD85k/ILT3 Protein (LIL-HM2B4) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | HM18; ILT3; ILT-3; LILRB4; LIR5; CD85K |
| Species | Human |
| Source | HEK293 |
| Accession | AAH26309 |
| Product Tag | C-hFc |
| Biotinylated | no |
| Exact Sequence | Gln22-Arg256 |
| Molecular Weight | The protein has a predicted MW of 52.6 kDa. Due to glycosylation, the protein migrates to 60-68 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
LIL-HM2B4: Human LILRB4/CD85k/ILT3 Protein (LIL-HM2B4)
LILRB4,also known as CD85k and LIR-5, ILT3, is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles.
Please remember our product information: Human LILRB4/CD85k/ILT3 Protein (LIL-HM2B4) catalog number: LIL-HM2B4 KACTUS Biosystems