Human LILRA4/CD85g Protein (LIL-HM4A4)
$243.00 – $810.00
KACTUS Biosystems Human LILRA4/CD85g Protein (LIL-HM4A4) (catalog No. LIL-HM4A4) is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Glu24-Asn446.
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Catalog No. | LIL-HM4A4 |
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Product Name | Human LILRA4/CD85g Protein (LIL-HM4A4) |
Supplier Name | KACTUS Biosystems |
Brand Name | KACTUS Biosystems |
Synonyms | CD85g; ILT7; ILT-7; ILT7MGC129598; LILRA4; MGC129597 |
Species | Human |
Source | HEK293 |
Accession | P59901 |
Product Tag | C-His-Avi |
Biotinylated | no |
Exact Sequence | Glu24-Asn446 |
Molecular Weight | The protein has a predicted MW of 49.5 kDa. Due to glycosylation, the protein migrates to 60-75 kDa based on Tris-Bis PAGE result. |
Form | Lyophilized |
Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
Endotoxin | Less than 1EU per μg by the LAL method. |
Shipping | Shipped at ambient temperature. |
Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.; -20 to -80°C for 3-6 months in unopened state after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
LIL-HM4A4: Human LILRA4/CD85g Protein (LIL-HM4A4)
LILRA4, also known as ILT7 and CD85g, is an approximately 60-70 kDa variably glycosylated transmembrane protein that regulates immune cell activation. Mature human LILRA4 consists of a 423 amino acid (aa) extracellular domain (ECD) with four immunoglobulin-like domains, a 21 aa transmembrane segment, and a 32 aa cytoplasmic domain.LILRA4 function coreceptor to limit the innate immune responses to viral infections; signaling occurs via FCER1G (PubMed:16735691, PubMed:19564354). Down-regulates the production of IFNA1, IFNA2, IFNA4, IFNB1 and TNF by plasmacytoid dendritic cells that have been exposed to influenza virus or cytidine-phosphate-guanosine (CpG) dinucleotides, indicating it functions as negative regulator of TLR7 and TLR9 signaling cascades.
Please remember our product information: Human LILRA4/CD85g Protein (LIL-HM4A4) catalog number: LIL-HM4A4 KACTUS Biosystems
Additional information
Ship from Country | USA |
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Size | 100 ug, 500 ug |