Human JAM-A Protein (JAM-HM10A)
$270.00 – $900.00
KACTUS Biosystems Human JAM-A Protein (JAM-HM10A) (catalog No. JAM-HM10A) is expressed from HEK293 with His tag at the C-Terminus.It contains Ser28-Val238.
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| Catalog No. | JAM-HM10A |
|---|---|
| Product Name | Human JAM-A Protein (JAM-HM10A) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | JAM-A; JAM-1; CD321; JAM; JCAM; JCAM1; KAT; PAM-1; F11 receptor; F11R; PAM-1KAT |
| Species | Human |
| Source | HEK293 |
| Accession | Q9Y624-1 |
| Product Tag | C-His |
| Biotinylated | no |
| Exact Sequence | Ser28-Val238. |
| Molecular Weight | The protein has a predicted MW of 24 kDa. Due to glycosylation, the protein migrates to 28-35 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
JAM-HM10A: Human JAM-A Protein (JAM-HM10A)
junctional adhesion molecule A (JAM-A), a cell adhesion molecule, is highly elevated in human GBM cancer stem cells and predicts poor patient prognosis. While JAM-A is also highly expressed in other cells in the tumor microenvironment, specifically microglia and macrophages,JAM-A functions to suppress pathogenic microglial activation in the female tumor microenvironment, highlighting an emerging role for sex differences in the GBM microenvironment and suggesting that sex differences extend beyond previously reported tumor cell-intrinsic differences.
Please remember our product information: Human JAM-A Protein (JAM-HM10A) catalog number: JAM-HM10A KACTUS Biosystems
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug, 500 ug |