Human Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein (ITG-HM4V6)
$337.50 – $1,125.00
KACTUS Biosystems Human Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein (ITG-HM4V6) (catalog No. ITG-HM4V6) is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Phe31-Val992(ITGAV) acidic tail & Gly22-Asn707(ITGB6) basic tail.
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| Catalog No. | ITG-HM4V6 |
|---|---|
| Product Name | Human Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein (ITG-HM4V6) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | Integrin alpha V beta 6; ITGAV&ITGB6 |
| Species | Human |
| Source | HEK293 |
| Accession | P06756-1(ITGAV)&P18564-1(ITGB6) |
| Product Tag | C-His-Avi |
| Biotinylated | no |
| Exact Sequence | Phe31-Val992(ITGAV) acidic tail & Gly22-Asn707(ITGB6) basic tail |
| Molecular Weight | The protein has a predicted MW of 114 kDa (ITGAV)&79.1 kDa (ITGB6). Due to glycosylation, the protein migrates to 90-150 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
ITG-HM4V6: Human Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein (ITG-HM4V6)
ITGAV&ITGB6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. ITGAV&ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1.
Please remember our product information: Human Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein (ITG-HM4V6) catalog number: ITG-HM4V6 KACTUS Biosystems