Human Integrin alpha 6 beta 1 (ITGA6&ITGB1) Heterodimer Protein (ITG-HM461)
$337.50 – $1,125.00
KACTUS Biosystems Human Integrin alpha 6 beta 1 (ITGA6&ITGB1) Heterodimer Protein (ITG-HM461) (catalog No. ITG-HM461) is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Phe24-Gly1012(ITGA6) acidic tail&GIn21-Asp728(ITGB1) basic tail.
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| Catalog No. | ITG-HM461 |
|---|---|
| Product Name | Human Integrin alpha 6 beta 1 (ITGA6&ITGB1) Heterodimer Protein (ITG-HM461) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | Integrin alpha 6 beta 1; ITGA6&ITGB1 |
| Species | Human |
| Source | HEK293 |
| Accession | P23229-2(ITGA6)&P05556-1(ITGB1) |
| Product Tag | C-His-Avi |
| Biotinylated | no |
| Exact Sequence | Phe24-Gly1012(ITGA6)acidic tail & GIn21-Asp728(ITGB1)basic tail |
| Molecular Weight | The protein has a predicted MW of 117.9 kDa(ITGA6)&83.2 kDa(ITGB1). Due to glycosylation, the protein migrates to 110-130 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
ITG-HM461: Human Integrin alpha 6 beta 1 (ITGA6&ITGB1) Heterodimer Protein (ITG-HM461)
Integrin alpha-6/beta-1 (ITGA6:ITGB1) is a receptor for laminin on platelets. Integrin alpha-6/beta-1 (ITGA6:ITGB1) is present in oocytes and is involved in sperm-egg fusion. Integrin alpha-6/beta-4 (ITGA6:ITGB4) is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome (By similarity). ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling
Please remember our product information: Human Integrin alpha 6 beta 1 (ITGA6&ITGB1) Heterodimer Protein (ITG-HM461) catalog number: ITG-HM461 KACTUS Biosystems