Human IL-23 alpha&IL-12 beta Protein (IL2-HM1AB)
$283.50 – $945.00
KACTUS Biosystems Human IL-23 alpha&IL-12 beta Protein (IL2-HM1AB) (catalog No. IL2-HM1AB) is expressed from HEK293 with His tag at the C-terminal.It contains Arg20-Pro189(IL-23 alpha) & Ile23-Ser328(IL-12 beta).
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| Catalog No. | IL2-HM1AB |
|---|---|
| Product Name | Human IL-23 alpha&IL-12 beta Protein (IL2-HM1AB) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Species | Human |
| Source | HEK293 |
| Accession | Q9NPF7(IL-23 alpha)&P29460(IL-12 beta) |
| Product Tag | C-His |
| Biotinylated | no |
| Exact Sequence | Arg20-Pro189(IL-23 alpha) & Ile23-Ser328(IL-12 beta) |
| Molecular Weight | The protein has a predicted MW of 19.77 kDa (IL-23 alpha) and 34.7 kDa (IL-12 beta). Due to glycosylation, the protein migrates to 23 kDa (IL-23 alpha) and 40-50 kDa (IL-12 beta) based on Tris-Bis PAGE result. |
| Form | Liquid |
| Formulation | Supplied as 0.22μm filtered solution in PBS (pH 7.4). |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped with dry ice. |
| Stability & Storage | Valid for 12 months from date of receipt when stored at -80°C.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
IL2-HM1AB: Human IL-23 alpha&IL-12 beta Protein (IL2-HM1AB)
The interleukin (IL)-12 family of cytokines, including IL12 and IL 23, play an important role in driving aberrant Th1 and Th17 immune responses in patients with Crohn’s disease (CD). Targeting this pathway has opened new avenues for therapeutic intervention. The balance of proinflammatory cytokines interleukin (IL)-12 and IL-23 plays a key role in shaping the development of antitumor or protumor immunity.
Please remember our product information: Human IL-23 alpha&IL-12 beta Protein (IL2-HM1AB) catalog number: IL2-HM1AB KACTUS Biosystems
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug, 500 ug |
