Human IGFBP-3R Protein (IGF-HM23R)
$270.00 – $900.00
KACTUS Biosystems Human IGFBP-3R Protein (IGF-HM23R) (catalog No. IGF-HM23R) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ser39-Arg204.
- Product Details
- Description
- Additional information
- More Offers
Catalog No. | IGF-HM23R |
---|---|
Product Name | Human IGFBP-3R Protein (IGF-HM23R) |
Supplier Name | KACTUS Biosystems |
Brand Name | KACTUS Biosystems |
Synonyms | IGFBP-3R; GFBP3R; LOC124446; TMEM219 |
Species | Human |
Source | HEK293 |
Accession | Q86XT9 |
Product Tag | C-hFc |
Biotinylated | no |
Exact Sequence | Ser39-Arg204 |
Molecular Weight | The protein has a predicted MW of 44.5 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result. |
Form | Lyophilized |
Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Purity | > 95% as determined by Tris-Bis PAGE |
Endotoxin | Less than 1EU per μg by the LAL method. |
Shipping | Shipped at ambient temperature. |
Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.;-20 to -80°C for 3-6 months in unopened state after reconstitution.;2-8°C for 2-7 days after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
IGF-HM23R: Human IGFBP-3R Protein (IGF-HM23R)
Insulin-like growth factor-binding protein-3 (IGFBP-3) is a multifunctional protein known for modulating mitogenic and metabolic actions of IGFs as well as exerting a variety of biological actions not involving IGF. IGFBP-3 inhibits airway inflammation and hyper-responsiveness via an IGF-independent mechanism that involves activation of IGFBP-3R signaling and cross-talk with NF-κB signaling. The IGFBP-3/IGFBP-3R system therefore plays a pivotal role in the pathogenesis of asthma and can serve as a newly identified potential therapeutic target for this debilitating disease.
Please remember our product information: Human IGFBP-3R Protein (IGF-HM23R) catalog number: IGF-HM23R KACTUS Biosystems
Additional information
Ship from Country | USA |
---|---|
Size | 100 ug, 500 ug |