Catalog No.	IDH-HE101
Product Name	Human IDH1 Protein (IDH-HE101)
Supplier Name	KACTUS Biosystems
Brand Name	KACTUS Biosystems
Species	Human
Source	E.coli
Accession	O75874
Product Tag	C-His
Biotinylated	no
Exact Sequence	Ser2-Leu414
Molecular Weight	The protein has a predicted MW of 47.35 kDa same as Tris-Bis PAGE result.
Form	Liquid
Formulation	Supplied as 0.22μm filtered solution in 50mM Tris, 200mM NaCl, 1mM DTT, 10% Glycerol (pH 7.5).
Purity	> 95% as determined by Tris-Bis PAGE;> 90% as determined by HPLC
Endotoxin	Less than 1EU per μg by the LAL method.
Shipping	Shipped with dry ice.
Stability & Storage	Valid for 12 months from date of receipt when stored at -80°C.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Note	Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline	Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

IDH-HE101: Human IDH1 Protein (IDH-HE101)

Isocitrate dehydrogenase (IDH) is a metabolic enzyme that converts isocitrate to α-ketoglutarate (α-KG). Genetic gain-of-function mutations in IDH1 and IDH2 confer a neomorphic activity that allow reduction of α -KG to (R)-2- hydroxyglutarate, the accumulation of which results in the development of cancers like low grade gliomas and leukemia.Isocitrate dehydrogenase 1 (IDH1) is the most frequently mutated metabolic gene in cancer.

Please remember our product information: Human IDH1 Protein (IDH-HE101) catalog number: IDH-HE101 KACTUS Biosystems

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