Human ICOS/CD278 (C136S, C137S) Protein (ICO-HM102)
$297.00 – $990.00
KACTUS Biosystems Human ICOS/CD278 (C136S, C137S) Protein (ICO-HM102) (catalog No. ICO-HM102) is expressed from HEK293 with His tag at the C-Terminus.It contains Glu21-Phe141(C136S,C137S).
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| Catalog No. | ICO-HM102 |
|---|---|
| Product Name | Human ICOS/CD278 (C136S, C137S) Protein (ICO-HM102) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | AILIM; CD278; CRP-1; CVID1; ICOS; MGC39850 |
| Species | Human |
| Source | HEK293 |
| Accession | Q9Y6W8-1 |
| Product Tag | C-His |
| Biotinylated | no |
| Exact Sequence | Glu21-Phe141(C136S,C137S) |
| Molecular Weight | The protein has a predicted MW of 14.8 kDa. Due to glycosylation, the protein migrates to 35-40 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
ICO-HM102: Human ICOS/CD278 (C136S, C137S) Protein (ICO-HM102)
Inducible co-stimulator (ICOS), also called AILIM (activiation-inducible lymphocyte immunomediatory molecule) and CRP-1 (CD28-related protein-1), is a member of the growing CD28 family of immune costimulatory receptors. Other family members are CD28, CTLA-4 and PD-1. Human ICOS is a homodimeric type I transmembrane protein consisting of 199 amino acids (aa) with a putative 20 aa signal sequence, a 121 aa extracellular domain, a 23 aa transmembrane region, and a 35 aa cytoplasmic domain.
Please remember our product information: Human ICOS/CD278 (C136S, C137S) Protein (ICO-HM102) catalog number: ICO-HM102 KACTUS Biosystems
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug, 500 ug |