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Human HMGB1 Protein (HMG-HM1B1)

Human HMGB1 Protein (HMG-HM1B1)

Human HMGB1 Protein (HMG-HM1B1)

$283.50$945.00

In stock

$283.50$945.00

KACTUS Biosystems Human HMGB1 Protein (HMG-HM1B1) (catalog No. HMG-HM1B1) is expressed from HEK293 with His tag at the C-Terminus.It contains Met1-Glu215.

SKU: HMG-HM1B1
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Catalog No. HMG-HM1B1
Product NameHuman HMGB1 Protein (HMG-HM1B1)
Supplier Name KACTUS Biosystems
Brand Name KACTUS Biosystems
Synonyms HMGB1; HMG1; HMG3; SBP-1; HMG-1
Species Human
Source HEK293
Accession P09429-1
Product Tag C-His
Biotinylated no
Exact Sequence Met1-Glu215
Molecular Weight The protein has a predicted MW of 26 kDa. Due to glycosylation, the protein migrates to 30-35 kDa based on Tris-Bis PAGE result.
Form Lyophilized
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per μg by the LAL method.
Shipping Shipped at ambient temperature.
Stability & Storage '-20 to -80°C for 12 months as supplied from date of receipt.; -20 to -80°C for 3-6 months in unopened state after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

HMG-HM1B1: Human HMGB1 Protein (HMG-HM1B1)

High-mobility group box 1 (HMGB1) is a ubiquitous nuclear protein that promotes inflammation when released extracellularly after cellular activation, stress, damage or death. HMGB1 operates as one of the most intriguing molecules in inflammatory disorders via recently elucidated signal and molecular transport mechanisms. Treatments based on antagonists specifically targeting extracellular HMGB1 have generated encouraging results in a wide number of experimental models of infectious and sterile inflammation.

Please remember our product information: Human HMGB1 Protein (HMG-HM1B1) catalog number: HMG-HM1B1 KACTUS Biosystems

Additional information

Ship from Country

USA

Size

100 ug, 500 ug

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