Human HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein (MHC-HM432T)
$675.00 – $2,700.00
KACTUS Biosystems Human HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein (MHC-HM432T) (catalog No. MHC-HM432T) isisassembled by biotinylated monomer and streptavidin.It contains Gly25-Thr305(HLA-A*02:03),Ile21-Met119(B2M) and FMNKFIYEI peptide.
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| Catalog No. | MHC-HM432T |
|---|---|
| Product Name | Human HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein (MHC-HM432T) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Species | Human |
| Source | HEK293 |
| Accession | AAA03604.1(HLA-A*02:03)&P61769(B2M)&FMNKFIYEI |
| Product Tag | C-His-Avi |
| Biotinylated | no |
| Exact Sequence | Gly25-Thr305(HLA-A*02:03),Ile21-Met119(B2M)and FMNKFIYEI peptide |
| Molecular Weight | The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
MHC-HM432T: Human HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein (MHC-HM432T)
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
Please remember our product information: Human HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein (MHC-HM432T) catalog number: MHC-HM432T KACTUS Biosystems